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glp-1 mechanism of action of [25] Glucagon-Like Peptide 1 Receptor Agonists
Although these neurobiological mechanisms are complex, both preclinical and clinical findings suggest the gut-brain peptide glucagon-like peptide-1 (GLP-1) as an important modulator of the neurobiological mechanisms underlying the development of AUD.12, 13, 14 Specifically, several GLP-1 receptor (GLP-1R) agonists suppress alcohol intake, alcohol-seeking behaviour and alcohol-induced activation of the mesolimbic dopamine system in male rodents,15, 16, 17, 18 a finding replicated in female rats
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Number of Vials:4 Vials (Differentiated Results)
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